Chemical name: 2-oxo-1-pyrrolidine acetamide
molecular formula C6H10N2O2
molecular weight 142.16
What is piracetam?
Piracetam, according to Wikipedia, is a grandfather of nootropic that appears to increase communication between the two hemispheres of the brain, and increases activity of the corpus callosum. Piracetam was the first substance to be classified as a nootropic; it is popular and commonly found worldwide, known in Russia, Europe, Asia, and South America as Nootropil or Lucetam. Piracetam has many other names, such as such as Pirroxil, Qropi, Cetam, Dinagen, Myocalm, Normabrain and Nootropil. Piracetam is the first and most popular of the racetam nootropics. It belongs to both the racetam and ampakine families. Both of these families carry great benefits. Its primary group, the racetams are known to influence the Acetylcholine system. Among the plethora of “cognitive enhancers” available on the market today, Piracetam is unregulated and stands above the rest as probably the most renown smart drug.
How piracetam works?
The racetam family of drugs are not well understood, however, Piracetam, along with other nootropic drugs in the racetam family, modulate the neurotransmitters glutamate and acetylcholine which are implicated in learning and memory. Piracetam is also a positive allosteric modulator of the AMPA receptor. In other words, Piracetam increases the activity of the AMPA receptor, which could increase synaptic plasticity and can therefore enhance memory and learning processes.
Piracetam improves the function of the neurotransmitter acetylcholine, through the muscarinic acetylcholine receptor. Because of this, Piracetam may deplete acetylcholine levels in the brain which could induce some of the side effects mentioned above. However, many take Piracetam without choline and do not experience side effects; in fact unnecessary choline supplementation may result in depression.
This drug also works by improving blood flow to the brain and by enhancing cross-hemispheric communication.
Benefits of taking piracetam supplements:
There are numerous health benefits associated with Piracetam. Like all other Nootropics, Piracetam boosts the central nervous system. It also stimulates the corpus callosum, the switchboard between the left and right hemispheres of the brain, thus facilitating increased communication between the two sides and enabling the brain to work at its optimum efficiency. Piracetam enhances the blood circulation to the brain cells and rejuvenates old and damaged neurons in the brain.
One of the most widely chronicled benefits of Piracetam is its ability to augment alertness, short-term memory, and attention span in both normal, healthy humans, and age-impaired persons. According to medical research, Piracetam causes improvements in memory and alertness by an average of 50%. It is clinically proven to reduce instances of depression by an average of 32% and increase memory by about 45% in patients suffering from Alzheimer’s disease and dementia. These patients have also experienced relief from conditions such as sleep disorders and paranoia. Even patients suffering from Down’s syndrome and dyslexia have benefitted immensely from the introduction of Piracetam in their treatment.
Piracetam helps to assuage learning difficulties associated with Attention Deficit Disorder (ADD), assists in the treatment of and speedy recovery from conditions such as hypoxia, alcohol consumption, stroke, epilepsy, tinnitus, vertigo, and sudden deafness. It is also known to reduce fatigue and improve athletic performance at high altitudes. Since it is a non-habit forming substace, its usage among students is common for improving concentration and focus.
Dosage for piracetam:
While there is no standard dosage for Piracetam, many find 1600 mg taken 3x daily to work for them. However, some may require a higher dosage, some a lower dosage. Some even find a micro dose, or a dosage lower than 100 mg, to work better than a higher dose. It generally takes more than 2 weeks for its effects to appear.
Because it is water-soluble, you do not have to take it with food. If you are taking powdered Piracetam then I recommend using orange juice to mask the taste as raw Piracetam is quite bitter. If you are taking capped Piracetam then you can just simply take it with water.
What is the best Nootropic to stack with Piracetam?
It is recommended you start off by taking Piracetam alone with no choline source. If you experience headache or brain fog then you can start taking a choline source. There are many choline supplements on the market. Some of them include:
CDP-Choline (or Citicoline)
CDP-Choline actually has some benefits of its own, including increasing focus, attention as well as energy. These effects are mediated by the increase of dopamine receptor density as well as acetylcholine receptor density in the brain.