What is Quercetin?
Quercetin is a flavonoid with antioxidant properties. This compound has many natural sources, including fruits like apples and grapefruits, certain types of nuts, green tea; it is one of the antioxidants associated with good health effects of red wine. Flavonoids like quercetin are generally considered to be very healthy, and supplements are often recommended to enhance basic health.
Molecular Formula : C15H10O7
Molecular Weight : 302.24
CAS Registry Number: 117-39-5
Benefits of taking Quercetin supplements:
Quercetin is used for treating conditions of the heart and blood vessels including «hardening of the arteries» (atherosclerosis), high cholesterol, high blood pressure, heart disease, and circulation problems. It is also used for diabetes, cataracts, hay fever, peptic ulcer, schizophrenia, inflammation, asthma, gout, viral infections, chronic fatigue syndrome (CFS), preventing cancer, for treating chronic infections of the prostate, improving the function of kidney transplants, and increasing exercise endurance.
Test tube studies published in the Journal of Allergy and Clinical Immunology in 1985 and in Progress in Clinical and Biological Research in 1986 found that the flavonoids contained in quercetin blocked histamine release and other activities in the body associated with allergic reactions that lead to hives, eczema, asthma and hay fever. Published in the Journal of Science, a 1977 study of rats with diabetes found that quercetin prevented cataract formation. A human double-blind clinical trial published in the Journal of Urology in 1999 revealed that taking quercetin supplements helped treat chronic prostatitis, a condition involving prostate inflammation in men. A 2000 test tube study published in the Alternative Medicine Review also found that quercetin’s antioxidant properties may offer anticancer effects. A double-blind clinical trial found that quercetin can help to treat interstitial cystitis symptoms, and the results of this trial were presented at the American Urological Association 2001 Annual Meeting. Finally, two 1985 studies published in the Journal of Medical Virology and the medical journal Experientia revealed that quercetin’s flavonoids have antiviral effects on herpes, polio and influenza viruses.
Quercetin may benefit those with heart disease. it inhibits the proliferation and migration of aortic smooth muscle cells, inhibits platelet aggregation, improves the health of the endothelium and protects vascular endothelial cells against oxidative and proinflammatory insults.
Quercetin exerts antihypertensive effects and reduces left ventricular hypertrophy, endothelial dysfunction, and the plasma and hepatic oxidative status in spontaneously hypertensive rats.
Quercetin in Skin Care
As an anti-inflammatory, quercetin has soothing, redness-reducing properties. A 2010 study showed that when applied topically, quercetin was a potent proteasome activator. In other words, it helped to rejuvenate middle-aged or dying cells and even stimulated the growth of new cells. In addition to helping skin cells function better, quercetin can diminish fine lines and wrinkles and improve the skin’s texture and elasticity.
Brain tissue and schizophrenia
Quercetin has potential for the treatment of neuroleptic-induced extrapyramidal side effects, such as from the drug haloperidol. Quercetin is a powerful antioxidant that may protect brain cells from damage.
Common cold, and immune health
Quercetin, a naturally occurring, powerful antioxidant found in red grapes, red wine, red apples, green tea and broccoli, appears to be one of the first plant compound proven in a double-blind, randomized, placebo-controlled clinical trial to reduce susceptibility to viral illnesses. Dr. David Nieman, a professor at Appalachian State University was the researcher and presented his findings at the southeastern regional meeting of the American College of Sports Medicine in Charlotte, N.C. Participants in the study — long-distance cyclists — ingested 1,000 milligrams of pure quercetin, combined with vitamin C and niacin.
Side effects and safety of Quercetin
side effects include upset stomach, nausea, diarrhea, headache, unusual and unpleasant tastes in the mouth, vomiting and loss of appetite. While these are considered the most common side effects associated with using this supplement, they only affect a small amount of users.
Dosage of Quercetin supplement:
The quantity of quercetin varies in different supplements, but anywhere from 500-1500 mg per day is a typical dosage for health benefits.