What is Tauroursodeoxycholic acid(TUDCA)?
Tauroursodeoxycholic acid, according to Wikipedia, is a bile salt that is found natrually occurring in the body, it usually exhist in the form of sodium salt. When regular bile salts reach the intestines, they can be metabolized by bacteria into UDCA and then later bound to a Taurinemolecule to become TUDCA. Bile is naturally synthesized via cholesterol, consisting of compounds including taurochenodeoxycholic acid, ursodeoxycholic acid, and chenodeoxycholic acid.
Relationship between TUDCA and UDCA
TUDCA is short for tauroursodeoxycholic acid, basically, a metabolite of the prescription drug ursodeoxycholic acid. UDCA is prescribed for the treatment of cholestatic liver disease. While UDCA is great for reversing liver disease, you can’t get it without a prescription not to mention, it’ll cost you a fortune to get. That’s where TUDCA comes in. Because it’s a metabolite of UDCA, TUDCA gives you great liver protection. With TUDCA, you’re getting a product that may be just as potent without a prescription or the crazy price of UDCA. So you’re thinking, what’s the big deal? I can take milk thistle and get the same benefits for cheaper. Not really. Milk thistle helps bile production, but it’s no comparison to the mighty TUDCA when you consider this fact: oral supplements of milk thistle just don’t absorb well.
Benefits of taking Tauroursodeoxycholic acid（TUDCA）
- Helps protect the liver
TUDCA is a supplement that is more effective than milk thistle for protecting and may even help to reverse liver damage. TUDCA supports bile flow to remove these toxic metabolites from the liver. In this way, TUDCA protects you against cholestasis to ensure cholesterol metabolism. Because TUDCA ensures that you’re breaking down fat, it helps to prevent fatty liver disease. It also protects the liver against cell death. Not only do you get liver protection, but you’ve got a built in cholesterol fighter when you take TUDCA.
- Promotes healthy cholesterol levels
Ursodeoxycholic acid (udca) is a secondary bile acid in the body. It also helps the digestive track breakdown cholesterol. It is the only FDA approved drug to treat cirrhosis. It has been shown to reduce jaundice and liver enzymes.
- Protects the eyes
bear bile — you guessed it, a natural source of Tauroursodeoxycholic acid（TUDCA） — has an over 3,000 yearlong history of being used to treat visual disorders. many of them can be treated and prevented by the administration of TUDCA and other bile-acids or bile-acid precursors, such as taurine.
Dosage of Tauroursodeoxycholic acid（TUDCA）
From the website of nutraoplanet, the dosage is 250mg daily. Usage of 500mg TUDCA daily for one year (in persons after liver transplants) was not assocaited with any adverse effects.
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